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OVOL1 Antibody

  • 货号：
    CSB-PA986690
  • 规格：
    ￥2024
  • 图片：
    • Western blot analysis of extracts from K562 cells and A549 cells, using OVOL1 antibody.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) OVOL1 Polyclonal antibody
  • Uniprot No.：
    O14753
  • 基因名：
    OVOL1
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from N-terminal of Human OVOL1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 克隆类型：
    Polyclonal
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the differentiation and/or maintenance of the urogenital system.
  • 基因功能参考文献：
    1. OVOL1 is an integral part of the aryl hydrocarbon receptor-mediated mechanism of Filaggrin expression in human keratinocytes. PMID: 28703805
    2. that the OVOL1-OVOL2 axis may actively contribute to cell differentiation and proliferation in the hair bulb PMID: 26873447
    3. OVOL1 is a regulator of trophoblast progenitor cell fate during human trophoblast development. PMID: 26504231
    4. KIF3A and OVOL1 are involved in the development of Atopic dermatitis in the Chinese pediatric population. PMID: 26127003
    5. OVOL1 may play an important role in human skin morphogenesis and tumorigenesis. PMID: 25509883
    6. Association of KIF3A, but not OVOL1 and ACTL9, with atopic eczema in Italian patients PMID: 23278845
    7. Molecular phylogeny of OVOL1, OVOL2 and OVOL3 genes illustrates a conserved C2H2 zinc finger domain coupled by hypervariable unstructured regions in humans and other species PMID: 22737237

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  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Expressed in fetal kidney, and also in adult pancreas and placenta. Not expressed in intestine, peripheral blood lymphocytes and ovary.
  • 数据库链接：

    HGNC: 8525

    OMIM: 602313

    KEGG: hsa:5017

    STRING: 9606.ENSP00000337862

    UniGene: Hs.134434