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OR51E1 Antibody

  • 货号：
    CSB-PA002137
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of HeLa cells using D-GPCR Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q8TCB6
  • 基因名：
    OR51E1
  • 别名：
    OR51E1; GPR164; OR51E1P; OR52A3P; POGR; PSGR2; Olfactory receptor 51E1; D-GPCR; G-protein coupled receptor 164; Olfactory receptor 52A3; Prostate-overexpressed G protein-coupled receptor; Prostate-specific G protein-coupled receptor 2
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human D-GPCR.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Odorant receptor.
  • 基因功能参考文献：
    1. Results suggest the involvement of OR51E1 in growth processes of PCa cells and its impact on AR-mediated signaling. These findings provide novel evidences to support the functional importance of ORs in PCa pathogenesis. PMID: 27374083
    2. These findings indicate that OR51E1 may play a role as metabolic regulator of cardiac function PMID: 28116519
    3. Olfactory receptor 51E1 as a novel target for diagnosis in somatostatin receptor-negative lung carcinoids. PMID: 23969981
    4. OR51E1 protein is a potential novel clinical tissue biomarker for small intestine neuroendocrine carcinomas. PMID: 23184910
    5. Results suggest that PSGR2 may be useful as a tissue marker and molecular target for the early detection and treatment of human prostate cancers. PMID: 16206286
    6. This publication uses 'GPR136' as a name for this gene. PMID: 12732197

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  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 组织特异性：
    Highly expressed in prostate. Very low levels may be detected in some other tissues, such as placenta, skeletal muscle, heart, ovary and testis. Up-regulated in prostate cancers.
  • 数据库链接：

    HGNC: 15194

    OMIM: 611267

    KEGG: hsa:143503

    STRING: 9606.ENSP00000380155

    UniGene: Hs.470038