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OR1D2 Antibody

  • 货号：
    CSB-PA020193
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    P34982
  • 基因名：
    OR1D2
  • 别名：
    OR1D2; OLFR1; Olfactory receptor 1D2; Olfactory receptor 17-4; OR17-4; Olfactory receptor OR17-6; Olfactory receptor-like protein HGMP07E
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Olfactory receptor 1D2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Odorant receptor which may be involved in sperm chemotaxis. Bourgeonal is a strong chemoattractant for sperm in vitro and is shown to be a strong agonist for OR1D2 in vitro. May also function in olfactory reception.
  • 基因功能参考文献：
    1. The present preliminary study seems to confirm the important role of OR1D2 both in nose and spermatozoa and may explain the idiopathic infertility of the study group. PMID: 23525651
    2. the homo-oligomerization status of the human OR1740 receptor and its involvement in receptor activation upon odorant ligand binding were addressed PMID: 21454689
    3. results indicate that hOR17-4 functions in human sperm chemotaxis and may be a critical component of the fertilization process PMID: 12663925
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein. Note=In spermatazoa is localized in the midpiece and is translocated to the head region upon receptor stimulation with bourgeonal.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 组织特异性：
    Expressed in testis. Expressed in spermatozoa (at protein level). Expressed in olfactory epithelium.
  • 数据库链接：

    HGNC: 8183

    OMIM: 164342

    KEGG: hsa:4991

    STRING: 9606.ENSP00000327585

    UniGene: Hs.532771