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OGDHL Antibody

  • 货号：
    CSB-PA016308GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9ULD0
  • 基因名：
    OGDHL
  • 别名：
    2-oxoglutarate dehydrogenase complex component E1-like antibody; 2-oxoglutarate dehydrogenase-like, mitochondrial antibody; Alpha-ketoglutarate dehydrogenase-like antibody; KIAA1290 antibody; OGDC-E1-like antibody; OGDHL antibody; OGDHL_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human OGDHL
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    2-oxoglutarate dehydrogenase (E1-like) component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDHC) which mediates the decarboxylation of alpha-ketoglutarate in the tricarboxylic acid cycle. The OGDHC complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) while reducing NAD(+) to NADH. The OGDHC complex is mainly active in the mitochondrion. Involved in the inhibition of cell proliferation and in apoptosis.
  • 基因功能参考文献：
    1. inactivation of OGDHL can contribute to cervical tumorigenesis via activation of the AKT signaling pathway and thus support it as an important anti-proliferative gene in cervical cancer. PMID: 23152800
  • 亚细胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Alpha-ketoglutarate dehydrogenase family
  • 组织特异性：
    Expressed in the brain and the liver.
  • 数据库链接：

    HGNC: 25590

    OMIM: 617513

    KEGG: hsa:55753

    STRING: 9606.ENSP00000363216

    UniGene: Hs.17860