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OAZ3 Antibody

  • 货号：
    CSB-PA016247LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) OAZ3 Polyclonal antibody
  • Uniprot No.：
    Q9UMX2
  • 基因名：
    OAZ3
  • 别名：
    Antizyme 3 antibody; AZ3 antibody; OAZ t antibody; OAZ3 antibody; OAZ3_HUMAN antibody; ODC-Az 3 antibody; Ornithine decarboxylase antizyme 3 antibody; RP11-98D18.13-004 antibody; Testicular secretory protein Li 31 antibody; TISP15 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Ornithine decarboxylase antizyme 3 protein (1-190AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，OAZ3 Antibody (CSB-PA016247LA01HU)，的标记方式是Non-conjugated。对于OAZ3 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA016247LB01HU OAZ3 Antibody, HRP conjugated ELISA
    FITC CSB-PA016247LC01HU OAZ3 Antibody, FITC conjugated
    Biotin CSB-PA016247LD01HU OAZ3 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimers. Does not target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity. Stabilizes AZIN2 by interfering with its ubiquitination. Involved in the translocation of AZNI2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol. Probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells.
  • 基因功能参考文献：
    1. Mutations in the OAZ3 gene are not a common cause of male infertility. PMID: 16542438
    2. antizyme expression requires programmed, ribosomal frameshifting PMID: 10781085
  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    ODC antizyme family
  • 组织特异性：
    Testis specific.
  • 数据库链接：

    HGNC: 8097

    OMIM: 605138

    KEGG: hsa:51686

    STRING: 9606.ENSP00000415904

    UniGene: Hs.713789