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NXF5 Antibody

  • 货号：
    CSB-PA016223LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: NXF5 antibody at 4µg/ml + HL60 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 46, 43, 20, 36, 35 kDa
      Observed band size: 46 kDa
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA016223LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA016223LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA016223LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NXF5 Polyclonal antibody
  • Uniprot No.：
    Q9H1B4
  • 基因名：
    NXF5
  • 别名：
    NXF5 antibody; TAPL1 antibody; Nuclear RNA export factor 5 antibody; TAP-like protein 1 antibody; TAPL-1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Nuclear RNA export factor 5 protein (1-200AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，NXF5 Antibody (CSB-PA016223LA01HU)，的标记方式是Non-conjugated。对于NXF5 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA016223LB01HU NXF5 Antibody, HRP conjugated ELISA
    FITC CSB-PA016223LC01HU NXF5 Antibody, FITC conjugated
    Biotin CSB-PA016223LD01HU NXF5 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in polarized cytoplasmic transport and localization of mRNA in neurons.
  • 基因功能参考文献：
    1. study of an Australian pedigree in which focal segmental glomerulosclerosis co-segregates with progressive heart block; study found 2 mutations NXF5-R113W and ALG13-T141L segregated with disease phenotype; predicted the NXF5 R113W mutation to be deleterious; cellular studies support a role in the stability and localization of the protein suggesting a causative role PMID: 23686279
    2. Mutations of the NXF5 gene is associated with X-linked mental retardation PMID: 12784308
  • 相关疾病：
    A chromosomal aberration involving NXF5 has been observed in one patient with a syndromic form of mental retardation and short stature. Pericentric inversion inv(X)(p21.1;q22) that interrupts NXF5.
  • 亚细胞定位：
    Cytoplasm. Nucleus. Note=Mainly localized in the cytoplasm of cells and more particularly in the cell body and neurites of hippocampal neurons. Although nuclear localization is also observed. Not detected at nuclear rim.
  • 蛋白家族：
    NXF family
  • 数据库链接：

    HGNC: 8075

    OMIM: 300319

    KEGG: hsa:55998

    STRING: 9606.ENSP00000426978

    UniGene: Hs.307077