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NUP50 Antibody

  • 中文名称：
    NUP50兔多克隆抗体
  • 货号：
    CSB-PA018458
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA018458(NUP50 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Hela cells, 293T cells, A549 cells, HT29 cells, Primary antibody: CSB-PA018458(NUP50 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他：

产品详情

  • Uniprot No.：
    Q9UKX7
  • 基因名：
    NUP50
  • 别名：
    50 kDa nucleoporin antibody; NPAP60 antibody; NPAP60L antibody; Nuclear pore associated protein 60L antibody; Nuclear pore complex protein Nup50 antibody; Nuclear pore-associated protein 60 kDa-like antibody; Nucleoporin 50 antibody; Nucleoporin 50kDa antibody; Nucleoporin Nup50 antibody; Nup50 antibody; NUP50_HUMAN antibody; PRO1146 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Fusion protein of Human NUP50
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with regulatory proteins of cell cycle progression including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.
  • 基因功能参考文献：
    1. Nucleoporin Nup50 stabilizes closed conformation of armadillo repeat 10 in importin alpha5. PMID: 22130666
    2. Results suggest that Npap60L and Npap60S function differently in nuclear protein import. PMID: 20016008
  • 亚细胞定位：
    Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side.
  • 组织特异性：
    Ubiquitous. Highest levels in testis, peripheral blood leukocytes and fetal liver.
  • 数据库链接：

    HGNC: 8065

    OMIM: 604646

    KEGG: hsa:10762

    STRING: 9606.ENSP00000345895

    UniGene: Hs.475103