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NUBPL Antibody

  • 货号：
    CSB-PA819450LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: NUBPL antibody at 1µg/ml + A431 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 35, 19 kDa
      Observed band size: 35 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA819450LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA819450LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NUBPL Polyclonal antibody
  • Uniprot No.：
    Q8TB37
  • 基因名：
    NUBPL
  • 别名：
    C14orf127 antibody; FLJ12660 antibody; huInd1 antibody; IND1 homolog antibody; Iron-sulfur protein NUBPL antibody; Nubpl antibody; NUBPL_HUMAN antibody; nucleotide binding protein like antibody; Nucleotide-binding protein-like antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Iron-sulfur protein NUBPL protein (39-319AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，NUBPL Antibody (CSB-PA819450LA01HU)，的标记方式是Non-conjugated。对于NUBPL Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA819450LB01HU NUBPL Antibody, HRP conjugated ELISA
    FITC CSB-PA819450LC01HU NUBPL Antibody, FITC conjugated
    Biotin CSB-PA819450LD01HU NUBPL Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). May deliver of one or more Fe-S clusters to complex I subunits.
  • 基因功能参考文献：
    1. huInd1 binds to the untranslated region of the TEM-1 mRNA at 3' site and thereby reducing the possibility of its endonucleolytic cleavage, resulting in over-expression of TEM-1. PMID: 25240856
    2. Inhibition of ERK suppressed the NUBPL-induced changes in EMT and cell motility. PMID: 28346728
    3. Our data show that NUBPL mutations are associated with a unique, consistent, and recognizable MRI pattern. PMID: 23553477
    4. Mutations in NUBPL is associated with complex I deficiency. PMID: 20818383
    5. These data identify huInd1 as a new assembly factor for human respiratory complex I with a possible role in the delivery of one or more Fe/S clusters to complex I subunits.[Ind1] PMID: 19752196

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  • 相关疾病：
    Mitochondrial complex I deficiency (MT-C1D)
  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    Mrp/NBP35 ATP-binding proteins family
  • 组织特异性：
    Highest expression in liver and kidney. expressed at significant levels in small intestine and brain (at protein level).
  • 数据库链接：

    HGNC: 20278

    OMIM: 252010

    KEGG: hsa:80224

    STRING: 9606.ENSP00000281081

    UniGene: Hs.288981