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NSUN7 Antibody

  • 货号:
    CSB-PA822769LA01HU
  • 规格:
    ¥440
  • 促销:
    小规格抗体限时一口价
  • 图片:
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA822769LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA822769LA01HU at dilution of 1:100
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) NSUN7 Polyclonal antibody
  • Uniprot No.:
    Q8NE18
  • 基因名:
    NSUN7
  • 别名:
    NSUN7Putative methyltransferase NSUN7 antibody; EC 2.1.1.- antibody; NOL1/NOP2/Sun domain family member 7 antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Recombinant Human Putative methyltransferase NSUN7 protein (1-300AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated

    本页面中的产品,NSUN7 Antibody (CSB-PA822769LA01HU),的标记方式是Non-conjugated。对于NSUN7 Antibody,我们还提供其他标记。见下表:

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA822769LB01HU NSUN7 Antibody, HRP conjugated ELISA
    FITC CSB-PA822769LC01HU NSUN7 Antibody, FITC conjugated
    Biotin CSB-PA822769LD01HU NSUN7 Antibody, Biotin conjugated ELISA
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA, IHC
  • 推荐稀释比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    May have S-adenosyl-L-methionine-dependent methyl-transferase activity.
  • 基因功能参考文献:
    1. mutant protein structures of Nsun7 indicated that the amino acid serine was converted to alanine, the structure of the helix, coil and strand was changed, and the protein folding and ligand binding sites were changed in samples from asthenospermic men with a transversion mutation in exon 7, indicating impairment of protein function. Because Nsun7 plays a role in sperm motility, mutation in exon 7 may lead to infertility. PMID: 24384068
    2. Our findings revealed that genetic polymorphisms in exon7 of the NSUN7 gene are not associated with asthenospermia in Chinese Han men. PMID: 26345859
    3. Nsun7 (A11337)-deletion mutation, causes reduction of its protein rate and associated with sperm motility defect in infertile men. PMID: 25702163
  • 蛋白家族:
    Class I-like SAM-binding methyltransferase superfamily, RsmB/NOP family
  • 数据库链接:

    HGNC: 25857

    KEGG: hsa:79730

    STRING: 9606.ENSP00000371201

    UniGene: Hs.479602