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NSUN5 Antibody

  • 货号：
    CSB-PA839386LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate
      All lanes: NSUN5 antibody at 2.7µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 47, 51, 37, 52, 43 kDa
      Observed band size: 47 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NSUN5 Polyclonal antibody
  • Uniprot No.：
    Q96P11
  • 基因名：
    NSUN5
  • 别名：
    FLJ10267 antibody; MGC986 antibody; NOL1 antibody; NOL1-related protein antibody; NOL1/NOP2/Sun domain family member 5 antibody; NOL1R antibody; NOP2/Sun domain family, member 5 antibody; NOP2/Sun domain family, member 5A antibody; NSUN5 antibody; NSUN5_HUMAN antibody; p120 antibody; Putative methyltransferase NSUN5 antibody; WBSCR20 antibody; WBSCR20A antibody; Williams Beuren syndrome chromosome region 20A antibody; Williams-Beuren syndrome chromosomal region 20A protein antibody; Williams-Beuren syndrome critical region protein 20 copy A antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Probable 28S rRNA (cytosine-C(5))-methyltransferase protein (362-466AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，NSUN5 Antibody (CSB-PA839386LA01HU)，的标记方式是Non-conjugated。对于NSUN5 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA839386LB01HU NSUN5 Antibody, HRP conjugated ELISA
    FITC CSB-PA839386LC01HU NSUN5 Antibody, FITC conjugated
    Biotin CSB-PA839386LD01HU NSUN5 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 3782 (m5C3782) in 28S rRNA. m5C3782 promotes protein translation without affecting ribosome biogenesis and fidelity. Required for corpus callosum and cerebral cortex development.
  • 基因功能参考文献：
    1. Characterization of two novel genes, WBSCR20 and WBSCR22, deleted in Williams-Beuren syndrome PMID: 11978965
  • 相关疾病：
    NSUN5 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.
  • 亚细胞定位：
    Nucleus, nucleolus.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, RsmB/NOP family
  • 组织特异性：
    Ubiquitous. Detected in placenta, heart and skeletal muscle.
  • 数据库链接：

    HGNC: 16385

    OMIM: 615732

    KEGG: hsa:55695

    STRING: 9606.ENSP00000309126

    UniGene: Hs.510927