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NOP2 Antibody

  • 货号：
    CSB-PA015938GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    P46087
  • 基因名：
    NOP2
  • 别名：
    NOP2 antibody; NOL1 antibody; NSUN1Probable 28S rRNA antibody; cytosine(4447)-C(5))-methyltransferase antibody; EC 2.1.1.- antibody; Nucleolar protein 1 antibody; Nucleolar protein 2 homolog antibody; Proliferating-cell nucleolar antigen p120 antibody; Proliferation-associated nucleolar protein p120 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Human NOP2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in ribosomal large subunit assembly. S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 4447 in 28S rRNA (Probable). May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation (Probable).
  • 基因功能参考文献：
    1. NOL1 represents a new route by which telomerase activates transcription of cyclin D1 gene, thus maintaining cell proliferation capacity PMID: 26906424
    2. p120 has an rRNA:5-Methylcytosine-Methyltransferase activity. PMID: 26196125
    3. Findings suggest a newly discovered role of Nop2 in both mature neurons and in cells possibly involved in the regeneration of nervous tissue PMID: 25481415
  • 亚细胞定位：
    Nucleus, nucleolus.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, RsmB/NOP family
  • 数据库链接：

    HGNC: 7867

    OMIM: 164031

    KEGG: hsa:4839

    STRING: 9606.ENSP00000382392

    UniGene: Hs.534334