NOMO1 Antibody
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) NOMO1 Polyclonal antibody
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Uniprot No.:Q15155
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基因名:NOMO1
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别名:Nodal modulator 1 antibody; NOMO 1 antibody; Nomo antibody; NOMO1 antibody; NOMO1_HUMAN antibody; PM5 antibody; pM5 protein antibody; pM5 protein telomeric copy antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human Nodal modulator 1 protein (918-1044AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
本页面中的产品,NOMO1 Antibody (CSB-PA015931LA01HU),的标记方式是Non-conjugated。对于NOMO1 Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA, WB, IHC, IF
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推荐稀释比:
Application Recommended Dilution WB 1:500-1:5000 IHC 1:20-1:200 IF 1:20-1:200 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Component of a ribosome-associated endoplasmic reticulum (ER) translocon complex involved in multi-pass membrane protein transport into the ER membrane and biogenesis. May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning, via its interaction with NCLN/Nicalin.
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基因功能参考文献:
- Microsatellite-Stable (MSS) CRC showed a very high proportion of homozygous loss of NOMO1 (54 of 59 cases, 91.5%), while the deletion was observed in only 7 out of 16 MSI cases. Deletion of NOMO1 is a molecular marker predominantly associated with CRC, particularly MSS subtypes. PMID: 28416736
- H19 gene could inhibit human trophoblast cell proliferation via encoding miR-675 that targeted NOMO1 downregulation. PMID: 22832245
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亚细胞定位:Endoplasmic reticulum membrane; Single-pass membrane protein.
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组织特异性:Expressed in colon tumor tissue and in adjacent normal colonic mucosa.
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数据库链接:
HGNC: 30060
OMIM: 609157
KEGG: hsa:23420
STRING: 9606.ENSP00000287667
UniGene: Hs.743963