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NOA1 Antibody

  • 中文名称：
    NOA1兔多克隆抗体
  • 货号：
    CSB-PA836715LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Jurkat whole cell lysate, Hela whole cell lysate, Mouse kidney tissue
      All lanes: NOA1 antibody at 3.4µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 79 kDa
      Observed band size: 79 kDa
    • IHC image of CSB-PA836715LA01HU diluted at 1:500 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NOA1 Polyclonal antibody
  • Uniprot No.：
    Q8NC60
  • 基因名：
    NOA1
  • 别名：
    NOA1 antibody; C4orf14 antibody; Nitric oxide-associated protein 1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Nitric oxide-associated protein 1 protein (42-174AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，NOA1 Antibody (CSB-PA836715LA01HU)，的标记方式是Non-conjugated。对于NOA1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA836715LB01HU NOA1 Antibody, HRP conjugated ELISA
    FITC CSB-PA836715LC01HU NOA1 Antibody, FITC conjugated
    Biotin CSB-PA836715LD01HU NOA1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:500-1:1000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP.
  • 基因功能参考文献：
    1. Our results uncovered an unexpected, mandatory detour of NOA1 through the nucleolus before uptake into mitochondria. PMID: 25072814
    2. This study indicates rhat C4orf14 is involved in 28S subunit biogenesis and mtDNA maintenance. PMID: 22447445
    3. The present study suggests a novel function for mAtNOS1 in regulating mitochondrial nitric oxide and calcium and inducing apoptosis of MCF-7 cells PMID: 18456285
  • 亚细胞定位：
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族：
    TRAFAC class YlqF/YawG GTPase family, NOA1 subfamily
  • 数据库链接：

    HGNC: 28473

    OMIM: 614919

    KEGG: hsa:84273

    STRING: 9606.ENSP00000264230

    UniGene: Hs.8715