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NME7 Antibody

  • 货号：
    CSB-PA897289LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: NME7 antibody at 12μg/ml + Mouse liver tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 43, 39 kDa
      Observed band size: 43 kDa
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA897289LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA897289LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NME7 Polyclonal antibody
  • Uniprot No.：
    Q9Y5B8
  • 基因名：
    NME7
  • 别名：
    MN23H7 antibody; NDK 7 antibody; NDK7_HUMAN antibody; NDP kinase 7 antibody; nm23 H7 antibody; nm23-H7 antibody; NME/NM23 family member 7 antibody; Nme7 antibody; Non metastatic cells 7 protein expressed in (nucleoside diphosphate kinase) antibody; Nucleoside diphosphate kinase 7 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Nucleoside diphosphate kinase 7 protein (1-150AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，NME7 Antibody (CSB-PA897289LA01HU)，的标记方式是Non-conjugated。对于NME7 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA897289LB01HU NME7 Antibody, HRP conjugated ELISA
    FITC CSB-PA897289LC01HU NME7 Antibody, FITC conjugated
    Biotin CSB-PA897289LD01HU NME7 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
  • 基因功能参考文献：
    1. Study provides evidence that the deleterious mutation in NME7, which results in deletion of amino acids necessary for its interaction with Gamma-tubulin ring complex associated with impaired left-right asymmetry manifested by Situs Inversus Totalis. PMID: 27060491
    2. RNA-seq analysis shows vast differences between the parent FGF2 grown, primed state cells, and NME7AB converted cells, but similarities to altered gene expression patterns reported by others generating naive-like stem cells via the use of biochemical inhibitors PMID: 26749426
    3. NME7 functions in the gamma-tubulin ring complex in a kinase-dependent manner to facilitate microtubule nucleation. PMID: 24807905
    4. Compared with wild-type betagamma nucleoside diphosphate kinase overexpression of Gbeta nucleoside diphosphate kinase suppressed basal cAMP formation up to 55%. PMID: 17363702
  • 蛋白家族：
    NDK family
  • 数据库链接：

    HGNC: 20461

    OMIM: 613465

    KEGG: hsa:29922

    STRING: 9606.ENSP00000356785

    UniGene: Hs.706952