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NME3 Antibody

  • 货号：
    CSB-PA614400ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA614400ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA614400ESR2HU at dilution of 1:100
    • Immunofluorescent analysis of PC-3 cells using CSB-PA614400ESR2HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NME3 Polyclonal antibody
  • Uniprot No.：
    Q13232
  • 基因名：
    NME3
  • 别名：
    c371H6.2 antibody; DR-nm23 antibody; Expressed in non metastatic cells 3 antibody; NDK 3 antibody; NDK3 antibody; NDK3_HUMAN antibody; NDP kinase 3 antibody; NDP kinase C antibody; NDPK C antibody; NDPKC antibody; NM23 H3 antibody; nm23-H3 antibody; NM23H3 antibody; NME 3 antibody; NME/NM23 nucleoside diphosphate kinase 3 antibody; Nme3 antibody; Non metastatic cells 3 protein expressed in antibody; Nucleoside diphosphate kinase 3 antibody; Nucleoside diphosphate kinase C antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Nucleoside diphosphate kinase 3 protein (20-169AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.
  • 基因功能参考文献：
    1. Thus Tip60 interacts with RNR and NME3 to provide site-specific synthesis of dNTP for facilitating DNA repair in serum-deprived cells which contain low levels of dNTPs. PMID: 26945015
    2. Down-regulated DR-nm23 expression is associated with invasion and metastasis in colorectal cancer. PMID: 23765094
    3. Among genes correlated to nodal metastatic progression, we verified in vitro that NM23-H3 reduced cell motility. PMID: 17900511
  • 蛋白家族：
    NDK family
  • 数据库链接：

    HGNC: 7851

    OMIM: 601817

    KEGG: hsa:4832

    STRING: 9606.ENSP00000219302

    UniGene: Hs.514065