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NMB Antibody

  • 中文名称：
    NMB兔多克隆抗体
  • 货号：
    CSB-PA015880GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    P08949
  • 基因名：
    NMB
  • 别名：
    NMB antibody; Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B] antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human NMB
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Stimulates smooth muscle contraction in a manner similar to that of bombesin.
  • 基因功能参考文献：
    1. Genetic clues to the mechanism by which MC4R, FTO, and NMB influences changes in BMI and obesity. PMID: 27634552
    2. Rs2292462 was associated with left ventricular hypertrophy in type 2 diabetic patients. PMID: 23879873
    3. There was no association between eating behaviour traits, or anthropometric variables, and NMB p.P73T polymorphism. PMID: 21527296
    4. TT genotype of the NMB rs3809508 polymorphism was associated with a higher risk of obesity and moreover, the effects of this polymorphism on anthropometric values were influenced by the maternal educational level. PMID: 20010906
    5. lysosomal degradation of neuromedin B is dependent on tripeptidyl peptidase-I PMID: 15158442
    6. NMB and its receptor are coexpressed by proliferating cells in which they act in an autocrine fashion with similar and modest potency in both normal and malignant colonic epithelial cells. PMID: 15528253
    7. Associated with eating behaviors PMID: 15585758
    8. REsults describe the expression of neuromedin B in adipose tissue and its regulation by changes in energy balance. PMID: 17766645
    9. No significant differences in the genotype distribution were demonstrated between normal weight and overweight/obese subjects PMID: 18271693

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Bombesin/neuromedin-B/ranatensin family
  • 数据库链接：

    HGNC: 7842

    OMIM: 162340

    KEGG: hsa:4828

    STRING: 9606.ENSP00000378089

    UniGene: Hs.386470