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NGFRAP1 Antibody

  • 货号：
    CSB-PA923759
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA923759(NGFRAP1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA923759(NGFRAP1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q00994
  • 基因名：
  • 别名：
    Bex antibody; BEX3 antibody; BEX3_HUMAN antibody; Brain expressed X linked 3 (mouse) homolog antibody; brain expressed; X-linked 3 antibody; Brain-expressed X-linked gene 3 antibody; Brain-expressed X-linked protein 3 antibody; DXS6984E antibody; HGR74 antibody; NADE antibody; Nerve growth factor receptor (TNFRSF16) associated protein 1 antibody; Nerve growth factor receptor associated protein 1 antibody; Nerve growth factor receptor-associated protein 1 antibody; NGFR-associated protein 1 antibody; NGFRAP1 antibody; Ovarian granulosa cell 13.0 kDa protein HGR74 antibody; ovarian granulosa cell protein (13kD) antibody; Ovarian granulosa cell protein antibody; p75NTR associated cell death executor antibody; p75NTR-associated cell death executor antibody; Protein BEX3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human NGFRAP1
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. May play an important role in the pathogenesis of neurogenetic diseases.
  • 基因功能参考文献：
    1. Results showed that BEX3 was overexpressed in nasopharyngeal carcinoma (NPC), and indicated a unique functional role of BEX3 in mediating the sensitivity of NPC cells to cisplatin. PMID: 28083995
    2. Structure-function analysis of NADE: identification of regions that mediate nerve growth factor-induced apoptosis PMID: 11830582
    3. suppresses cell growth in vivo, when expressed in cultured cells PMID: 12739005
    4. DRG-1 may contribute to the dopamine-induced cell growth, which is negatively regulated by NADE PMID: 16777077
  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    BEX family
  • 组织特异性：
    Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
  • 数据库链接：

    HGNC: 13388

    OMIM: 300361

    KEGG: hsa:27018

    STRING: 9606.ENSP00000299872

    UniGene: Hs.448588