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NEUROG2 Antibody

  • 货号：
    CSB-PA887960LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: U87 whole cell lysate, SH-SY5Y whole cell lysate, Rat lung tissue
      All lanes: NEUROG2 antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 29 kDa
      Observed band size: 29, 60 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NEUROG2 Polyclonal antibody
  • Uniprot No.：
    Q9H2A3
  • 基因名：
    NEUROG2
  • 别名：
    Atoh 4 antibody; Atoh4 antibody; bHLHa8 antibody; Class A basic helix-loop-helix protein 8 antibody; Math 4A antibody; Math4A antibody; MGC antibody; MGC46562 antibody; NEUROG 2 antibody; NEUROG2 antibody; Neurogenin-2 antibody; Neurogenin2 antibody; NGN 2 antibody; NGN-2 antibody; NGN2 antibody; NGN2_HUMAN antibody; Protein atonal homolog 4 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Rat
  • 免疫原：
    Recombinant Human Neurogenin-2 protein (194-262AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，NEUROG2 Antibody (CSB-PA887960LA01HU)，的标记方式是Non-conjugated。对于NEUROG2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA887960LB01HU NEUROG2 Antibody, HRP conjugated ELISA
    FITC CSB-PA887960LC01HU NEUROG2 Antibody, FITC conjugated
    Biotin CSB-PA887960LD01HU NEUROG2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Transcriptional regulator. Involved in neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3').
  • 基因功能参考文献：
    1. Study shows neurogenin 2 enhances the generation of patient-specific induced neuronal cells. PMID: 25912433
    2. Results show that neurogenin-1 and -2 drive homogeneous differentiation of human stem cells into bipolar neurons in 4 days in defined media. PMID: 25403753
    3. human embryonic progenitors expressing neurogenin-2 stimulate axonal sprouting and improve motor recovery after severe spinal cord injury PMID: 21209909
    4. Novel compound heterozygous variants (Gly56Arg and Asp206Glu) were found in a 91-year normal male, suggesting that mutations in the coding region of the NEUROG2 gene play little or no role in the development of PD. PMID: 19879328
    5. expression of Ngn2 during the differentiation of neuronl human embryo stem cells. PMID: 17784840
    6. Rat and mouse species-dependent differences of Nurr1 and Ngn2 actions in dopamine neuron differentiation. PMID: 18242186

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  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 13805

    OMIM: 606624

    KEGG: hsa:63973

    STRING: 9606.ENSP00000317333

    UniGene: Hs.744415