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NAPA Antibody

  • 货号：
    CSB-PA015447LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: NAPA antibody at 7µg/ml
      Lane 1: 293T whole cell lysate
      Lane 2: Hela whole cell lysate
      Lane 3: K562 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 34 kDa
      Observed band size: 34 kDa
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA015447LA01HU at dilution of 1:100
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA015447LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NAPA Polyclonal antibody
  • Uniprot No.：
    P54920
  • 基因名：
  • 别名：
    Alpha soluble NSF attachment protein antibody; Alpha-soluble NSF attachment protein antibody; N ethylmaleimide sensitive factor attachment protein alpha antibody; N-ethylmaleimide-sensitive factor attachment protein alpha antibody; napA antibody; NSF attachment protein alpha antibody; SNAA_HUMAN antibody; SNAP alpha antibody; SNAP-alpha antibody; SNAPA antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Alpha-soluble NSF attachment protein (1-295AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，NAPA Antibody (CSB-PA015447LA01HU)，的标记方式是Non-conjugated。对于NAPA Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA015447LB01HU NAPA Antibody, HRP conjugated ELISA
    FITC CSB-PA015447LC01HU NAPA Antibody, FITC conjugated
    Biotin CSB-PA015447LD01HU NAPA Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (Probable). Together with GNA12 promotes CDH5 localization to plasma membrane.
  • 基因功能参考文献：
    1. alphaSNAP is mainly expressed in the neuron brain tissue of patients with temporal lobe epilepsy. Its blood levels were significantly lower in these patients. alphaSNAP levels may increase epilepsy susceptibility. PMID: 26156199
    2. data implicates beta1 integrin, FAK, and paxillin in mediating the observed pro-adhesive effects of alphaSNAP. These results reveal novel roles for alphaSNAP in regulating ECM adhesion and motility of epithelial cells. PMID: 24311785
    3. Study revealed a novel role for alphaSNAP as a negative regulator of autophagy that acts by enhancing mTOR signaling and regulating the integrity of the Golgi complex. PMID: 23187805
    4. novel roles for alphaSNAP in promoting the formation of epithelial adherens junctions and tight junctions by controlling golgi-dependent expression and trafficking of junctional proteins. PMID: 22485163
    5. The most N-terminal part of BKV agnoprotein is involved in the interaction with alpha-SNAP PMID: 21931730
    6. a novel role for alphaSNAP in promoting epithelial cell survival by unique mechanisms involving regulation of Bcl-2 expression and Golgi biogenesis PMID: 22194596
    7. alpha-SNAP plays a key role in the acrosome reaction. PMID: 15542541
    8. G alpha12 interaction with alphaSNAP induces VE-cadherin localization at endothelial junctions and regulates barrier function PMID: 15980433

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  • 亚细胞定位：
    Cell membrane; Peripheral membrane protein.
  • 蛋白家族：
    SNAP family
  • 数据库链接：

    HGNC: 7641

    OMIM: 603215

    KEGG: hsa:8775

    STRING: 9606.ENSP00000263354

    UniGene: Hs.126938