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NABP1 Antibody

  • 货号：
    CSB-PA850257HA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: NABP1 antibody at 2µg/ml
      Lane 1: Hela whole cell lysate
      Lane 2: Jurkat whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 23, 14, 15 kDa
      Observed band size: 23 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NABP1 Polyclonal antibody
  • Uniprot No.：
    Q96AH0
  • 基因名：
    NABP1
  • 别名：
    FLJ13624 antibody; FLJ22833 antibody; hSSB2 antibody; MGC111163 antibody; Nabp1 antibody; Nucleic acid-binding protein 1 antibody; OBFC2A antibody; Oligonucleotide/oligosaccharide binding fold containing 2A antibody; Oligonucleotide/oligosaccharide binding fold containing protein 2A antibody; Oligonucleotide/oligosaccharide-binding fold-containing protein 2A antibody; Sensor of single strand DNA complex subunit B2 antibody; Sensor of single-strand DNA complex subunit B2 antibody; Sensor of ssDNA subunit B2 antibody; Single stranded DNA binding protein 2 antibody; Single-stranded DNA-binding protein 2 antibody; SOSB2_HUMAN antibody; SOSS B2 antibody; SOSS complex subunit B2 antibody; SOSS-B2 antibody; SSB2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human SOSS complex subunit B2 protein (1-204AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，NABP1 Antibody (CSB-PA850257HA01HU)，的标记方式是Non-conjugated。对于NABP1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA850257HB01HU NABP1 Antibody, HRP conjugated ELISA
    FITC CSB-PA850257HC01HU NABP1 Antibody, FITC conjugated
    Biotin CSB-PA850257HD01HU NABP1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
  • 基因功能参考文献：
    1. SNPs rs11903757, with closest proximity to NABP1 and SDPR, and rs966423 in DIRC3, were associated with survival in laryngeal squamous cell carcinoma patients. PMID: 27793000
    2. hSSB1 and hSSB2 form two separate complexes with similar structures, and both complexes participate in DNA damage response. PMID: 19605351
  • 亚细胞定位：
    Nucleus. Note=Localizes to nuclear foci following DNA damage.
  • 蛋白家族：
    SOSS-B family, SOSS-B2 subfamily
  • 数据库链接：

    HGNC: 26232

    OMIM: 612103

    KEGG: hsa:64859

    STRING: 9606.ENSP00000403683

    UniGene: Hs.591610