N Antibody
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货号:CSB-PA318492LA01JAM
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规格:¥440
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促销:
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图片:
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其他:
产品详情
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产品名称:Rabbit anti-Junin mammarenavirus N Polyclonal antibody
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Uniprot No.:P14239
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基因名:
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别名:N antibody; Nucleoprotein antibody; EC 3.1.13.- antibody; Nucleocapsid protein antibody; Protein N antibody
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宿主:Rabbit
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反应种属:Junin mammarenavirus
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免疫原:Recombinant Junin mammarenavirus Nucleoprotein protein (1-564AA)
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免疫原种属:Junin mammarenavirus
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标记方式:Non-conjugated
本页面中的产品,N Antibody (CSB-PA318492LA01JAM),的标记方式是Non-conjugated。对于N Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA, WB
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推荐稀释比:
Application Recommended Dilution WB 1:500-1:5000 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation. Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
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亚细胞定位:Virion. Host cytoplasm.
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蛋白家族:Arenaviridae nucleocapsid protein family
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