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MYO16 Antibody

  • 货号：
    CSB-PA008306
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q9Y6X6
  • 基因名：
    MYO16
  • 别名：
    MYO16 antibody; KIAA0865 antibody; MYO16B antibody; NYAP3 antibody; Unconventional myosin-XVI antibody; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3 antibody; Unconventional myosin-16 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Myosin XVI.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development. Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis.
  • 基因功能参考文献：
    1. KIRREL3 interacting proteins MAP1B and MYO16 are potential candidates for intellectual disability and autism spectrum disorder. PMID: 25902260
    2. This study suggest that common variation within MYO16 may contribute to the genetic liability to schizophrenia. PMID: 24141571
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; NYAP family
  • 数据库链接：

    HGNC: 29822

    OMIM: 615479

    KEGG: hsa:23026

    STRING: 9606.ENSP00000349145

    UniGene: Hs.656587