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MYL3 Antibody

  • 货号：
    CSB-PA015310DSR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: MYL3 antibody at 3.78 μg/ml
      Lane 1: Mouse heart tissue
      Lane 2: Mouse skeletal muscle tissue
      Lane 3: Rat heart tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 22 kDa
      Observed band size: 22 kDa
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA015310DSR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) MYL3 Polyclonal antibody
  • Uniprot No.：
    P08590
  • 基因名：
  • 别名：
    Cardiac myosin light chain 1 antibody; CMH8 antibody; CMLC1 antibody; ELC of myosin antibody; Essential light chain of myosin antibody; MLC1SB antibody; MLC1V antibody; MYL3 antibody; MYL3_HUMAN antibody; Myosin light chain 1 antibody; Myosin light chain 1 slow twitch muscle B/ventricular isoform antibody; Myosin light chain 1 slow, B antibody; Myosin light chain 3 antibody; Myosin, light chain 1, ventricular antibody; myosin, light chain 3, alkali, ventricular, skeletal, slow antibody; myosin, light polypeptide 3, alkali antibody; myosin, light polypeptide 3, alkali, ventricular, skeletal, slow antibody; OTTHUMP00000165922 antibody; Slow skeletal ventricular myosin alkali light chain 3 antibody; slow-twitch muscle B/ventricular isoform antibody; Ventricular/slow twitch myosin alkali light chain antibody; VLC1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human Myosin light chain 3 protein (1-195AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Regulatory light chain of myosin. Does not bind calcium.
  • 基因功能参考文献：
    1. In Familial Hypertrophic Cardiomyopathy, the MYL3 Arg94His variant was associated with high disease penetrance and substantial interventricular septal hypertrophy PMID: 26443374
    2. N-fragment is the binding domain of human ventricular LC1, whereas the C-fragment serves as a functional domain, which may be more involved in the modulation of the actin-activated ATPase activity of myosin PMID: 14516912
    3. Cell-permeable peptide containing the 15 amino acid N-terminal peptide from human ventricular light chain-1 (VLC-1) enhanced myocardial contractility. PMID: 17717642
  • 相关疾病：
    Cardiomyopathy, familial hypertrophic 8 (CMH8)
  • 数据库链接：

    HGNC: 7584

    OMIM: 160790

    KEGG: hsa:4634

    STRING: 9606.ENSP00000292327

    UniGene: Hs.517939