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MYH1 Antibody

  • 货号：
    CSB-PA015289ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA015289ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA015289ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) MYH1 Polyclonal antibody
  • Uniprot No.：
    P12882
  • 基因名：
    MYH1
  • 别名：
    adult 1 antibody; MYH1 antibody; MYH1_HUMAN antibody; MyHC-2x antibody; MyHC-IIx/d antibody; Myosin heavy chain 1 antibody; Myosin heavy chain 2x antibody; Myosin heavy chain antibody; Myosin heavy chain IIx/d antibody; Myosin-1 antibody; skeletal muscle antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Myosin-1 protein (1-100AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Muscle contraction.
  • 基因功能参考文献：
    1. Transcriptional levels of MHC-I, MHC-IIa, and MHC-IIb in denervation groups were significantly down-regulated compared with controls PMID: 26059207
    2. Myosin isoforms impact single-fiber force generation and may lead to alterations in whole skeletal muscle performance. PMID: 25567808
    3. adaptive response to reduced masticatory load was lower numerical and area proportion of MyHC-1 expressing fibres and higher numerical proportion of hybrid fibres in edentulous compared with dentate subjects PMID: 22489880
    4. The human genioglossus muscle is composed of conventional myosin heavy chain isoforms and 3 primary myosin heavy chain phenotypes. PMID: 22337492
    5. the expression levels of the MHC genes are associated with age and both PGC-1alpha and PGC-1beta and indicate that the MHC genes may to some extent be used to determine fibre-type composition in human skeletal muscle. PMID: 21470888
    6. we found a higher percentage of fibers expressing fast MyHC IIx in tetraplegic cerebral palsy PMID: 17916367
    7. Modular organization of phylogenetically conserved domains controlling developmental regulation of the human skeletal gene family PMID: 11971910
    8. frequency of fibers expressing myosin heavy chain (MyHC) IIx increased in spastic paresis PMID: 17196619
    9. Patients on hemodialysis demonstrate relatively fewer type 1 and consequently more type 2x fibres, with a corresponding change in MHC isoforms (MHC I and MHC IIX) in the skeletal muscle. PMID: 17853024

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  • 亚细胞定位：
    Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
  • 蛋白家族：
    TRAFAC class myosin-kinesin ATPase superfamily, Myosin family
  • 数据库链接：

    HGNC: 7567

    OMIM: 160730

    KEGG: hsa:4619

    STRING: 9606.ENSP00000226207

    UniGene: Hs.689619