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MYBL1 Antibody

  • 货号：
    CSB-PA010296
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    P10243
  • 基因名：
    MYBL1
  • 别名：
    A-Myb antibody; AMYB antibody; MGC120059 antibody; MGC120061 antibody; Myb related protein A antibody; Myb-like protein 1 antibody; Myb-related protein A antibody; MYBA_HUMAN antibody; MYBL1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human A-Myb.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Transcription factor that specifically recognizes the sequence 5'-YAAC[GT]G-3'. Acts as a master regulator of male meiosis by promoting expression of piRNAs: activates expression of both piRNA precursor RNAs and expression of protein-coding genes involved in piRNA metabolism. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity. Transcriptional activator of SOX30.
  • 基因功能参考文献：
    1. Low MYBL1 expression is associated with colon cancer. PMID: 28096468
    2. Our study defines new molecular subclasses of ACC characterized by MYBL1 rearrangements and 5'-NFIB gene fusions. PMID: 26631609
    3. Thus, the LIMD1-MYBL1 Index had considerable clinical value for DLBCL subtype classification and prognosis. PMID: 25940947
    4. analysis of genetic alterations in MYBL1 in diffuse pediatric low-grade gliomas PMID: 23633565
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Expressed in a variety of lymphoid and solid tumor lines cultured in vitro.
  • 数据库链接：

    HGNC: 7547

    OMIM: 159405

    KEGG: hsa:4603

    STRING: 9606.ENSP00000429633

    UniGene: Hs.445898