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MVD Antibody

  • 货号：
    CSB-PA595344
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA595344(MVD Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    P53602
  • 基因名：
    MVD
  • 别名：
    Diphosphomevalonate decarboxylase antibody; FP17780 antibody; MDDase antibody; Mevalonate (diphospho) decarboxylase antibody; Mevalonate (diphospho)decarboxylase antibody; Mevalonate pyrophosphate decarboxylase antibody; MPD antibody; Mvd antibody; MVD1_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human MVD
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.
  • 基因功能参考文献：
    1. functional importance of R161 and N17 in the binding and orientation of mevalonate diphosphate PMID: 18823933
  • 相关疾病：
    Porokeratosis 7, multiple types (POROK7)
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Diphosphomevalonate decarboxylase family
  • 组织特异性：
    Expressed in heart, skeletal muscle, lung, liver, brain, pancreas, kidney and placenta.
  • 数据库链接：

    HGNC: 7529

    OMIM: 603236

    KEGG: hsa:4597

    STRING: 9606.ENSP00000301012

    UniGene: Hs.252457