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MURJ Antibody

  • 货号：
    CSB-PA365235XA01ENV
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: MURJ antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 16.8 kDa
      Observed band size: 17 kDa
  • 其他：

产品详情

  • Uniprot No.：
    P0AF16
  • 基因名：
    MURJ
  • 别名：
    Lipid II flippase MurJ (Peptidoglycan biosynthesis protein MurJ) murJ mviN yceN b1069 JW1056
  • 反应种属：
    Japanese encephalitis virus
  • 免疫原：
    Recombinant Escherichia coli (strain K12) MURJ protein
  • 免疫原种属：
    Escherichia coli (strain K12)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Protein G
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
  • 基因功能参考文献：
    1. The crystal structure of substrate-free MurJ reveals an inward-open conformation. High-throughput mutagenesis and next-generation sequencing assessed mutational tolerance at every amino acid in the protein, providing a detailed functional and structural map for the enzyme and identifying sites for inhibitor development. A rocker-switch model for lipid II transport was supported. PMID: 29891673
    2. From these data, s hypothesize that some charged residues in the cavity region of MurJ homologs are required for interaction with lipid II and/or energy coupling during transport. PMID: 25225268
    3. MurJ is the lipid II flippase in Escherichia coli. PMID: 25013077
  • 亚细胞定位：
    Cell inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    MurJ/MviN family
  • 数据库链接：

    KEGG: ecj:JW1056

    STRING: 316385.ECDH10B_1140