Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. MSC Antibody

MSC Antibody

  • 货号：
    CSB-PA003336
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of Jurkat cells using Musculin Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    O60682
  • 基因名：
    MSC
  • 别名：
    ABF-1 antibody; ABF1 antibody; Activated B cell factor 1 antibody; Activated B-cell factor 1 antibody; bHLHa22 antibody; Class A basic helix-loop-helix protein 22 antibody; Msc antibody; MUSC_HUMAN antibody; Musculin antibody; MYOR antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human Musculin.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Transcription repressor capable of inhibiting the transactivation capability of TCF3/E47. May play a role in regulating antigen-dependent B-cell differentiation.
  • 基因功能参考文献：
    1. this study shows that musculin inhibits human T-helper 17 cell response to interleukin 2 by controlling STAT5B activity PMID: 28612433
    2. results demonstrate that ABF-1 facilitates formation of memory B cells but prevents plasma cell differentiation. PMID: 25070843
    3. role in repressing lymphotoxin alpha PMID: 15052269
    4. ABF-1 is frequently silenced by promoter methylation in follicular lymphoma, diffuse large B-cell lymphoma and Burkitt's lymphoma. PMID: 18368067
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Expressed in lymphoid tissues, B-cell lines and activated B-cells.
  • 数据库链接：

    HGNC: 7321

    OMIM: 603628

    KEGG: hsa:9242

    STRING: 9606.ENSP00000321445

    UniGene: Hs.442619