Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. MRPS18B Antibody

MRPS18B Antibody

  • 货号：
    CSB-PA014892GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9Y676
  • 基因名：
    MRPS18B
  • 别名：
    28S ribosomal protein S18-2 antibody; 28S ribosomal protein S18b antibody; 28S ribosomal protein S18b; mitochondrial antibody; C6orf14 antibody; DKFZp564H0223 antibody; HSPC 183 antibody; HSPC183 antibody; mitochondrial antibody; Mitochondrial ribosomal protein S18 2 antibody; Mitochondrial ribosomal protein S18B antibody; MRP S18 2 antibody; MRP S18 b antibody; MRP S18b antibody; MRP-S18-2 antibody; MRP-S18-b antibody; MRPS 18B antibody; MRPS18 2 antibody; Mrps18-b antibody; MRPS18B antibody; PTD017 antibody; RT18B_HUMAN antibody; S18amt antibody; S18mt-b antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human MRPS18B
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Together, these data suggest that the S18-2 protein induces epithelial to mesenchymal cell transition through the TWIST2/E-cadherin signalling and, consequently, CXCR4-mediated migration of prostate cancer cells. PMID: 29396484
    2. Evolutionary trace analysis showed that the S18-2 protein is mutated at the higher rate in tumors, compared with S18-1 and S18-3. The one of the most conserved residues in the S18-2 protein sequence, Gly132, is often mutated in colorectal cancer. PMID: 27489352
    3. We conclude that high expression of S18-2 and free E2F...1might be a good set of prognostic markers for endometrial cancer PMID: 26959119
    4. Studies suggest that mitochondrial ribosomal protein S18-2 protein, together with the retinoblastoma protein (RB), plays a crucial role in the control on cell stemness and differentiation. PMID: 28361860
    5. S18-2 is a newly identified oncoprotein that may be involved in cancerogenesis PMID: 26023799
    6. EBNA-6 {ebna-3c} binds to MRPS18-2 , and targets it to the nucleus; binding targets the small pocket of pRb, which is a site of interaction with E2F1. The MRPS18-2 competes with the binding of E2F1 to pRb, thereby raising the level of free E2F1 PMID: 18391203

    显示更多

    收起更多

  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    Bacterial ribosomal protein bS18 family, Mitochondrion-specific ribosomal protein mS40 subfamily
  • 数据库链接：

    HGNC: 14516

    OMIM: 611982

    KEGG: hsa:28973

    STRING: 9606.ENSP00000259873

    UniGene: Hs.655329