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MRPL12 Antibody

  • 货号：
    CSB-PA298637
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA298637(MRPL12 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA298637(MRPL12 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: 293T cells, Primary antibody: CSB-PA298637(MRPL12 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
  • 其他：

产品详情

  • Uniprot No.：
    P52815
  • 基因名：
    MRPL12
  • 别名：
    39S ribosomal protein L12 antibody; 39S ribosomal protein L12, mitochondrial antibody; 5c5-2 antibody; FLJ60124 antibody; L12mt antibody; MGC8610 antibody; mitochondrial antibody; Mitochondrial ribosomal protein L12 antibody; MRP-L12 antibody; MRP-L31/34 antibody; MRPL12 antibody; MRPL7 antibody; MRPL7/L12 antibody; RM12_HUMAN antibody; RPML12 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human MRPL12
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    As a component of the mitochondrial large ribosomal subunit, it plays a role in mitochondrial translation. Associates with mitochondrial RNA polymerase to activate transcription.
  • 基因功能参考文献：
    1. knock-down of MRPL12 by RNA interference results in instability of POLRMT. PMID: 26586915
    2. This mutation resulted in a decreased steady-state level of MRPL12 protein. PMID: 23603806
    3. the MRPL12 interaction with POLRMT is likely part of a novel regulatory mechanism that coordinates mitochondrial transcription with translation PMID: 17337445
  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    Bacterial ribosomal protein bL12 family
  • 数据库链接：

    HGNC: 10378

    OMIM: 602375

    KEGG: hsa:6182

    STRING: 9606.ENSP00000333837

    UniGene: Hs.109059