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MRI1 Antibody

  • 货号：
    CSB-PA014799GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9BV20
  • 基因名：
    MRI1
  • 别名：
    EI2BL antibody; M1Pi antibody; Mediator of RhoA-dependent invasion antibody; Methylthioribose 1 phosphate isomerase 1 antibody; Methylthioribose 1 phosphate isomerase homolog antibody; Methylthioribose-1-phosphate isomerase antibody; MGC3207 antibody; MRDI antibody; mri1 antibody; MTNA antibody; MTNA_HUMAN antibody; MTR-1-P isomerase antibody; S methyl 5 thioribose 1 phosphate isomerase 1 antibody; S-methyl-5-thioribose-1-phosphate isomerase antibody; Translation initiation factor eIF 2B antibody; Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein antibody; Ypr118w antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human MRI1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.
  • 基因功能参考文献：
    1. Data indicate that the structural elements in MRDI distal from the MTR-1-P catalytic site are responsible for the invasion phenotype. PMID: 23859498
    2. Identification of MRI1, encoding translation initiation factor eIF-2B subunit alpha/beta/delta-like protein, as a candidate locus for infantile epilepsy with severe cystic degeneration of the brain. PMID: 23124037
  • 亚细胞定位：
    Nucleus. Cytoplasm. Cell projection. Note=Primarily nuclear, but cytoplasmic in cancer cells, with enrichment at leading edge of the plasma membrane in late stage tumor cells.
  • 蛋白家族：
    EIF-2B alpha/beta/delta subunits family, MtnA subfamily
  • 数据库链接：

    HGNC: 28469

    OMIM: 615105

    KEGG: hsa:84245

    STRING: 9606.ENSP00000040663

    UniGene: Hs.439370