MPI Antibody
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) MPI Polyclonal antibody
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Uniprot No.:P34949
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基因名:MPI
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别名:ody; CDG1B antibody; FLJ39201 antibody; Mannose 6 phosphate isomerase antibody; Mannose-6-phosphate isomerase antibody; MANNOSEPHOSPHATE ISOMERASE antibody; MGC94106 antibody; MPI antibody; MPI_HUMAN antibody; Phosphohexomutase antibody; phosphomannose isomerase 1 antibody; Phosphomannose isomerase antibody; PMI antibody
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宿主:Rabbit
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反应种属:Human, Mouse
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免疫原:Recombinant Human Mannose-6-phosphate isomerase protein (1-423AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:Antigen Affinity Purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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产品提供形式:Liquid
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应用范围:ELISA, WB, IHC
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推荐稀释比:
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相关产品
靶点详情
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功能:Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
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基因功能参考文献:
- This work provides mechanistic evidence by which mannose phosphate isomerase loss induces p53, and identifies mannose phosphate isomerase as a novel regulator of p53 and Warburg metabolism. PMID: 28644127
- Phosphomannose isomerase inhibitors improve N-glycosylation in selected phosphomannomutase-deficient fibroblasts PMID: 21949237
- The mannose-6-phosphate-enzyme complex is developed and the key residues involved in the ligand binding are determined. Our results suggest a hydride transfer mechanism of alpha-hydrogen between the C1 and C2 positions. PMID: 16488169
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相关疾病:Congenital disorder of glycosylation 1B (CDG1B)
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亚细胞定位:Cytoplasm.
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蛋白家族:Mannose-6-phosphate isomerase type 1 family
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组织特异性:Expressed in all tissues, but more abundant in heart, brain and skeletal muscle.
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数据库链接:
HGNC: 7216
OMIM: 154550
KEGG: hsa:4351
STRING: 9606.ENSP00000318318
UniGene: Hs.75694