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MOCS2 Antibody

  • 货号：
    CSB-PA014706LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: MOCS2 antibody at 2µg/ml + Jurkat whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 21 kDa
      Observed band size: 21 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) MOCS2 Polyclonal antibody
  • Uniprot No.：
    O96007
  • 基因名：
    MOCS2
  • 别名：
    MOCS2 antibody; MCBPE antibody; MOCO1 antibody; Molybdopterin synthase catalytic subunit antibody; EC 2.8.1.12 antibody; MOCO1-B antibody; Molybdenum cofactor synthesis protein 2 large subunit antibody; Molybdenum cofactor synthesis protein 2B antibody; MOCS2B antibody; Molybdopterin-synthase large subunit antibody; MPT synthase large subunit antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Molybdopterin synthase catalytic subunit protein (1-188AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，MOCS2 Antibody (CSB-PA014706LA01HU)，的标记方式是Non-conjugated。对于MOCS2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA014706LB01HU MOCS2 Antibody, HRP conjugated ELISA
    FITC CSB-PA014706LC01HU MOCS2 Antibody, FITC conjugated
    Biotin CSB-PA014706LD01HU MOCS2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
  • 基因功能参考文献：
    1. analysis of sites within MOCS2 where mutations cause molybdenum cofactor deficiency PMID: 12732628
    2. There was undisturbed production of both transcripts, while Western blot analysis demonstrated that MOCS2B, the large subunit, is unstable in the absence of MOCS2A. PMID: 16737835
    3. We reported here an infant with MoCD who presented with hypoxic ischaemic encephalopathy and identified a novel mutation, c.130C>T in cDNA of the MOCS2 gene from the infant. PMID: 17158010
  • 相关疾病：
    Molybdenum cofactor deficiency, complementation group B (MOCODB)
  • 亚细胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    MoaE family, MOCS2B subfamily
  • 组织特异性：
    Highest levels are found in heart and skeletal muscle. Lower levels are present in brain, kidney and pancreas. Very low levels are found in lung and peripheral blood leukocytes.
  • 数据库链接：

    HGNC: 7193

    OMIM: 252160

    KEGG: hsa:4338

    STRING: 9606.ENSP00000380157

    UniGene: Hs.163645