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MLN Antibody

  • 货号：
    CSB-PA014638GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    P12872
  • 基因名：
    MLN
  • 别名：
    MAP antibody; MGC138519 antibody; MLN antibody; MOTI_HUMAN antibody; Motilin-associated peptide antibody; Promotilin antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Human MLN
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
  • 基因功能参考文献：
    1. Hemodialysis improves upper GI symptoms and gastric slow waves in CKD patients. An increase in ghrelin and a decrease in GLP-1 might be involved in the HD-induced improvement in gastric slow waves. PMID: 28566304
    2. motilin-induced phase III contractions signal hunger in healthy subjects and that this system is disturbed in morbidly obese patients--{REVIEW} PMID: 26660537
    3. Motilin stimulates growth hormone secretion and regulates interdigestive migrating contractions and fasting motor patterns in the gastrointestinal tract. [REVIEW] PMID: 22632857
    4. Motilin may directly influence adipocyte functions by stimulating energy storage. PMID: 21771971
    5. Ghrelin covaried with motilin in plasma in irritable bowel syndrome (IBS) but not in plasma from healthy subjects. This suggests the two peptides act together in IBS. PMID: 20338210
    6. Plasma levels of motilin were studied in 16 untreated Celiac disease patients and in an age-matched control group of 18 healthy subjects by radioimmunoassay and by high-performance liquid chromatography (HPLC). PMID: 12732349
    7. Ghrelin and motilin are cosecreted from a prominent endocrine cell population in the small intestine. PMID: 17595255
    8. The abnormal excretion of hormonal factors is closely related to gallstone formation PMID: 18234640
    9. About 35.9% of the patients with a T tube after cholecystectomy and choledochotomy have duodenal-biliary reflux. Most of them have sphincter of Oddi hypomotility and the decreased level of plasma motilin and serum gastrin. PMID: 18609694

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Motilin family
  • 数据库链接：

    HGNC: 7141

    OMIM: 158270

    KEGG: hsa:4295

    STRING: 9606.ENSP00000388825

    UniGene: Hs.2813