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MIOX Antibody

  • 货号：
    CSB-PA866220LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: MIOX antibody at 6µg/ml + Mouse kidney tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 34, 25 kDa
      Observed band size: 34 kDa
    • Immunoprecipitating MIOX in Mouse kidney tissue
      Lane 1: Rabbit control IgG instead of CSB-PA866220LA01HU in Mouse kidney tissue. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
      Lane 2: CSB-PA866220LA01HU (8µg) + Mouse kidney tissue (500µg)
      Lane 3: Mouse kidney tissue (10µg)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) MIOX Polyclonal antibody
  • Uniprot No.：
    Q9UGB7
  • 基因名：
    MIOX
  • 别名：
    0610009I10Rik antibody; AI314022 antibody; Aldehyde reductase-like 6 antibody; ALDRL6 antibody; C85427 antibody; Inositol oxygenase antibody; Kidney-specific protein 32 antibody; KSP32 antibody; MGC90217 antibody; MI oxygenase antibody; miox antibody; MIOX_HUMAN antibody; Myo-inositol oxygenase antibody; Renal-specific oxidoreductase antibody; RSOR antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Inositol oxygenase protein (1-285AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，MIOX Antibody (CSB-PA866220LA01HU)，的标记方式是Non-conjugated。对于MIOX Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA866220LB01HU MIOX Antibody, HRP conjugated ELISA
    FITC CSB-PA866220LC01HU MIOX Antibody, FITC conjugated
    Biotin CSB-PA866220LD01HU MIOX Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IP
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IP 1:200-1:2000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Our results suggest that serum MIOX levels do not change in polycystic ovary syndrome. It was, therefore, concluded that myoinositol deficiency observed in PCOS was not related to the level of MIOX enzyme which cleaves myoinositol. PMID: 29187000
    2. these findings highlight the epigenetic regulation of MIOX in the pathogenesis of diabetic tubulopathy. PMID: 28208054
    3. Data suggest that MIOX expression/activity is up-regulated in kidneys tubules during oxidative stress (as in obesity and diabetic nephropathy); up-regulation of MIOX activity is related to phosphorylation of serine/threonine residues. PMID: 26578517
    4. results demonstrated that the polymorphism (rs761745) in the promoter region of myo-inositol oxygenase(MIOX) gene may be associated with the development of type 1 diabetes mellitus in our studied population PMID: 19896870
    5. Molecular cloning and characterization of myo-inositol oxygenase as a 33kDa protein. PMID: 15504367
    6. expression of MIOX is up-regulated by a positive feedback mechanism where xylitol, one of the products of MI catabolism via the glucuronate-xylulose pathway, induces an overexpression of MIOX PMID: 15778219
    7. myo-inositol oxygenase (MIOX) PMID: 11716759

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Myo-inositol oxygenase family
  • 组织特异性：
    Kidney specific.
  • 数据库链接：

    HGNC: 14522

    OMIM: 606774

    KEGG: hsa:55586

    STRING: 9606.ENSP00000216075

    UniGene: Hs.129227