MINPP1 Antibody
产品详情
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Uniprot No.:Q9UNW1
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基因名:MINPP1
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别名:3 antibody; 4 antibody; 5)-tetrakisphosphate 3-phosphatase antibody; 5)P(4) 3-phosphatase antibody; DKFZp564L2016 antibody; HIPER1 antibody; Inositol (1 antibody; inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase antibody; Ins(1 antibody; ins(1,3,4,5)P(4) 3-phosphatase antibody; MINP1_HUMAN antibody; Minpp1 antibody; MINPP2 antibody; MIPP antibody; Multiple inositol polyphosphate histidine phosphatase, 1 antibody; Multiple inositol polyphosphate phosphatase 1 antibody; multiple inositol polyphosphate phosphatase 2 antibody
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宿主:Rabbit
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反应种属:Human,Mouse,Rat
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免疫原:Synthesized peptide derived from the Internal region of Human MIPP.
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
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抗体亚型:IgG
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纯化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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产品提供形式:Liquid
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应用范围:WB, IHC, ELISA
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推荐稀释比:
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:10000 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相关产品
靶点详情
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功能:Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy.
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基因功能参考文献:
- Minpp1 exhibits characteristics of a stress responsive molecule during Endoplasmic reticulum stress-induced apoptosis PMID: 27038811
- By RNA knockdown, we identified secreted and lysosome targeted MINPP1 (multiple inositol-polyphosphate phosphatase 1), the mammalian 3-phytase, to be essentially involved both in extracellular and in lysosomal InsP6 dephosphorylation PMID: 23186306
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相关疾病:Thyroid cancer, non-medullary, 2 (NMTC2)
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亚细胞定位:Endoplasmic reticulum lumen.
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蛋白家族:Histidine acid phosphatase family, MINPP1 subfamily
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组织特异性:Widely expressed with highest levels in kidney, liver and placenta.
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数据库链接:
HGNC: 7102
OMIM: 188470
KEGG: hsa:9562
STRING: 9606.ENSP00000361064
UniGene: Hs.121260
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