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MIA2 Antibody

  • 货号：
    CSB-PA512374
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of HEPG2 cells using MIA2 Polyclonal Antibody diluted at 1:500. Secondary antibody was diluted at 1:20000
    • Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200
    • Immunohistochemical analysis of paraffin-embedded human-pancreas, antibody was diluted at 1:200
    • Immunohistochemical analysis of paraffin-embedded human-pancreas, antibody was diluted at 1:200
  • 其他：

产品详情

  • Uniprot No.：
    Q96PC5
  • 基因名：
    MIA2
  • 别名：
    FLJ22404 antibody; Melanoma inhibitory activity 2 antibody; Melanoma inhibitory activity protein 2 antibody; Mia2 antibody; MIA2_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from MIA2 at AA range: 361-410
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB,ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-2000
    ELISA 1:10000-20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. Plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum. Thereby, may play a role in cholesterol and triglyceride homeostasis. Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PREB/SEC12 at the endoplasmic reticulum exit sites.
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Single-pass membrane protein.
  • 蛋白家族：
    MIA/OTOR family
  • 组织特异性：
    Highly expressed in liver and weakly in testis. Expression was higher in patients with severe fibrosis or inflammation and chronic hepatitis. Isoform 1 is specifically expressed in lung, testis, small intestine, colon, pancreas, kidney, liver and prostate
  • 数据库链接：

    HGNC: 18432

    OMIM: 608001

    KEGG: hsa:4253

    STRING: 9606.ENSP00000280082

    UniGene: Hs.287694