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MED4 Antibody

  • 货号：
    CSB-PA865098LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescent analysis of A549 cells using CSB-PA865098LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) MED4 Polyclonal antibody
  • Uniprot No.：
    Q9NPJ6
  • 基因名：
    MED4
  • 别名：
    Activator-recruited cofactor 36 kDa component antibody; ARC36 antibody; DRIP36 antibody; FLJ10956 antibody; HSPC126 antibody; med4 antibody; MED4_HUMAN antibody; Mediator complex subunit 4 antibody; Mediator of RNA polymerase II transcription subunit 4 antibody; Mediator of RNA polymerase II transcription, subunit 4 homolog antibody; OTTHUMP00000018390 antibody; OTTHUMP00000018391 antibody; OTTHUMP00000018392 antibody; RP11-90M2.2 antibody; TRAP/SMCC/PC2 subunit p36 subunit antibody; TRAP36 antibody; VDRIP antibody; Vitamin D3 receptor-interacting protein complex 36 kDa component antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Mediator of RNA polymerase II transcription subunit 4 protein (167-270AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，MED4 Antibody (CSB-PA865098LA01HU)，的标记方式是Non-conjugated。对于MED4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA865098LB01HU MED4 Antibody, HRP conjugated ELISA
    FITC CSB-PA865098LC01HU MED4 Antibody, FITC conjugated
    Biotin CSB-PA865098LD01HU MED4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
  • 基因功能参考文献：
    1. retinoblastoma RB1 -/- cells cannot survive in the absence of MED4, both in vitro and in orthotopic xenograft models in vivo, therefore identifying MED4 as a survival gene in retinoblastoma. PMID: 24858910
    2. Our findings suggest that Vitamin D Receptor polymorphisms may be associated with nasal carriage of S. aureus in individuals with type 1 diabetes. PMID: 19411183
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Mediator complex subunit 4 family
  • 数据库链接：

    HGNC: 17903

    OMIM: 605718

    KEGG: hsa:29079

    STRING: 9606.ENSP00000258648

    UniGene: Hs.181112