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MED30 Antibody

  • 货号：
    CSB-PA013663GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q96HR3
  • 基因名：
    MED30
  • 别名：
    MED30 antibody; MED30_HUMAN antibody; Mediator complex subunit 30 antibody; Mediator of RNA polymerase II transcription subunit 30 antibody; THRAP6 antibody; Thyroid hormone receptor-associated protein 6 antibody; Thyroid hormone receptor-associated protein complex 25 kDa component antibody; TRAP/Mediator complex component TRAP25 antibody; Trap25 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human MED30
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
  • 基因功能参考文献：
    1. MED30 seems to be involved in the progression of the renal cell carcinoma (RCC). PMID: 29661722
    2. Knockdown of MED30 led to reduction of the tumour parameters proliferation, migration, and invasion in the bladder cancer (BCa) cell lines. PMID: 29187445
    3. analysis of a novel transcript of MED30, termed MED30 short (MED30s) generated by alternative splicing PMID: 20493979
    4. Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s. PMID: 11909976
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Mediator complex subunit 30 family
  • 组织特异性：
    Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.
  • 数据库链接：

    HGNC: 23032

    OMIM: 610237

    KEGG: hsa:90390

    STRING: 9606.ENSP00000297347

    UniGene: Hs.492612