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MED20 Antibody

  • 货号：
    CSB-PA862046LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA862046LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA862046LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA862046LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) MED20 Polyclonal antibody
  • Uniprot No.：
    Q9H944
  • 基因名：
    MED20
  • 别名：
    MED20 antibody; TRFP antibody; Mediator of RNA polymerase II transcription subunit 20 antibody; Mediator complex subunit 20 antibody; TRF-proximal protein homolog antibody; hTRFP antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Mediator of RNA polymerase II transcription subunit 20 protein (1-212AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，MED20 Antibody (CSB-PA862046LA01HU)，的标记方式是Non-conjugated。对于MED20 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA862046LB01HU MED20 Antibody, HRP conjugated ELISA
    FITC CSB-PA862046LC01HU MED20 Antibody, FITC conjugated
    Biotin CSB-PA862046LD01HU MED20 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
  • 基因功能参考文献：
    1. Our analyses revealed no apparent differences in protein expression profiles of SRBs in central and peripheral regions of human donor tissues, indicating that carotenoid-binding proteins rather than transporters are likely to mediate selective accumulation of carotenoids into the macula. PMID: 28947101
    2. We identified the first and homozygous mutation (p.Gly114Ala) in the Mediator subunit 20 gene (MED20) in siblings presenting with infantile-onset spasticity and childhood-onset dystonia, progressive basal ganglia degeneration, and brain atrophy PMID: 25446406
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Mediator complex subunit 20 family
  • 数据库链接：

    HGNC: 16840

    OMIM: 612915

    KEGG: hsa:9477

    STRING: 9606.ENSP00000265350

    UniGene: Hs.278434