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ME3 Antibody

  • 货号：
    CSB-PA006739
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of RAW264.7 cells using ME3 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q16798
  • 基因名：
    ME3
  • 别名：
    ME3NADP-dependent malic enzyme antibody; mitochondrial antibody; NADP-ME antibody; EC 1.1.1.40 antibody; Malic enzyme 3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human ME3.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. ATP inhibition is proposed to be determined by the electrostatic potential involving the positive charge on the side chain of Lys346 PMID: 18959763
    2. Studies demonstrate that the Lys57 residue plays dual functional roles in the structural integrity of the allosteric site and in the subunit-subunit interaction at the dimer interface of m-NAD(P)-ME. PMID: 19236308
    3. human c-NADP-ME exists mainly as a tetramer, whereas human m-NAD(P)-ME exists as a mixture of dimers and tetramers PMID: 19416979
  • 亚细胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Malic enzymes family
  • 组织特异性：
    Expressed predominantly in organs with a low-division rate.
  • 数据库链接：

    HGNC: 6985

    OMIM: 604626

    KEGG: hsa:10873

    STRING: 9606.ENSP00000352657

    UniGene: Hs.199743