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MCIDAS Antibody

  • 货号：
    CSB-PA518689LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA518689LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) MCIDAS Polyclonal antibody
  • Uniprot No.：
    D6RGH6
  • 基因名：
    MCIDAS
  • 别名：
    IDAS antibody; Mci antibody; MCI_HUMAN antibody; Multicilin antibody; Protein Idas antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Multicilin protein (3-110AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，MCIDAS Antibody (CSB-PA518689LA01HU)，的标记方式是Non-conjugated。对于MCIDAS Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA518689LB01HU MCIDAS Antibody, HRP conjugated ELISA
    FITC CSB-PA518689LC01HU MCIDAS Antibody, FITC conjugated
    Biotin CSB-PA518689LD01HU MCIDAS Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1.
  • 基因功能参考文献：
    1. MCIDAS mutations result in a mucociliary clearance disorder with reduced generation of multiple motile cilia.MCIDAS regulates CCNO and FOXJ1 expression. PMID: 25048963
    2. The properties of the Idas-Geminin complex suggest it as the functional form of Idas and provide a possible mechanism to modulate Geminin activity PMID: 24064211
    3. Idas as a novel Geminin binding partner, implicated in cell cycle progression, and a putative regulator of proliferation-differentiation decisions during development. PMID: 21543332
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Geminin family
  • 数据库链接：

    HGNC: 40050

    OMIM: 614086

    KEGG: hsa:345643

    STRING: 9606.ENSP00000426359

    UniGene: Hs.394578