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MAST1 Antibody

  • 货号：
    CSB-PA897529LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA897529LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA897529LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA897529LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品描述：
    MAST1 polyclonal antibody CSB-PA897529LA01HU was produced in the rabbit immunized by using the Recombinant Human Microtubule-associated serine/threonine-protein kinase 1 protein (687-879AA) as the immunogen. The target protein MAST1 is essential for correct brain development, and appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Diseases associated with MAST1 include Mega-Corpus-Callosum Syndrome With Cerebellar Hypoplasia And Cortical Malformations and Cerebellar Hypoplasia.
    This Rabbit anti-Homo sapiens (Human) MAST1 Polyclonal antibody was tested in the ELISA, IHC and IF applications. The non-conjugated IgG got purified by protein G and reached up to 95% in purity. It only reacts with the MAST1 proteins of human-origin and may be used to detect the endogenous levels of MAST1 protein.
  • 产品名称：
    Rabbit anti-Homo sapiens (Human) MAST1 Polyclonal antibody
  • Uniprot No.：
    Q9Y2H9
  • 基因名：
    MAST1
  • 别名：
    9430008B02Rik antibody; KIAA0973 antibody; MAST 1 antibody; MAST1 antibody; MAST1_HUMAN antibody; Microtubule associated serine/threonine kinase 1 antibody; Microtubule associated serine/threonine protein kinase 1 antibody; Microtubule-associated serine/threonine-protein kinase 1 antibody; SAST 124 antibody; SAST 170 antibody; SAST antibody; SAST170 antibody; Syntrophin associated serine/threonine kinase antibody; Syntrophin associated serine/threonine protein kinase antibody; Syntrophin-associated serine/threonine-protein kinase antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Microtubule-associated serine/threonine-protein kinase 1 protein (687-879AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，MAST1 Antibody (CSB-PA897529LA01HU)，的标记方式是Non-conjugated。对于MAST1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA897529LB01HU MAST1 Antibody, HRP conjugated ELISA
    FITC CSB-PA897529LC01HU MAST1 Antibody, FITC conjugated
    Biotin CSB-PA897529LD01HU MAST1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Microtubule-associated protein essential for correct brain development. Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins.
  • 基因功能参考文献：
    1. Overexpression of MAST1 or MAST2 gene fusions has a proliferative effect both in vitro and in vivo in breast cancer cell lines. PMID: 22101766
    2. Discusses cloning of Sast, the mouse ortholog of human MAST1. PMID: 10404183
    3. Discusses cloning of Sast124, the rat ortholog of MAST1. PMID: 12614677
  • 亚细胞定位：
    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite.
  • 蛋白家族：
    Protein kinase superfamily, AGC Ser/Thr protein kinase family
  • 组织特异性：
    Expressed in fetal brain.
  • 数据库链接：

    HGNC: 19034

    OMIM: 612256

    KEGG: hsa:22983

    STRING: 9606.ENSP00000251472

    UniGene: Hs.227489