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LTN1 Antibody

  • 货号：
    CSB-PA026646LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA026646LA01HU diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA026646LA01HU diluted at 1:100 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) LTN1 Polyclonal antibody
  • Uniprot No.：
    O94822
  • 基因名：
    LTN1
  • 别名：
    LTN1 antibody; C21orf10 antibody; C21orf98 antibody; KIAA0714 antibody; RNF160 antibody; ZNF294 antibody; HSPC087E3 ubiquitin-protein ligase listerin antibody; EC 2.3.2.27 antibody; RING finger protein 160 antibody; RING-type E3 ubiquitin transferase listerin antibody; Zinc finger protein 294 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human E3 ubiquitin-protein ligase listerin protein (462-591AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，LTN1 Antibody (CSB-PA026646LA01HU)，的标记方式是Non-conjugated。对于LTN1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA026646LB01HU LTN1 Antibody, HRP conjugated ELISA
    FITC CSB-PA026646LC01HU LTN1 Antibody, FITC conjugated
    Biotin CSB-PA026646LD01HU LTN1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product.
  • 基因功能参考文献：
    1. E3 ligase listerin accesses nascent polypeptides stalled at the Sec61 translocon via a gap in the ribosome-translocon junction near the Sec61 lateral gate. PMID: 25877867
    2. Results show that Listerin specificity for nascent chain-60S complexes depends on nuclear export mediator factor. PMID: 25578875
  • 亚细胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    LTN1 family
  • 数据库链接：

    HGNC: 13082

    OMIM: 613083

    KEGG: hsa:26046

    STRING: 9606.ENSP00000373846

    UniGene: Hs.288773