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LRCH1 Antibody

  • 货号：
    CSB-PA897471LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: LRCH1 antibody at 15µg/ml + Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 81, 78, 85 kDa
      Observed band size: 81 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA897471LA01HU at dilution of 1:100
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA897471LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) LRCH1 Polyclonal antibody
  • Uniprot No.：
    Q9Y2L9
  • 基因名：
    LRCH1
  • 别名：
    LRCH1 antibody; CHDC1 antibody; KIAA1016 antibody; Leucine-rich repeat and calponin homology domain-containing protein 1 antibody; Calponin homology domain-containing protein 1 antibody; Neuronal protein 81 antibody; NP81 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Leucine-rich repeat and calponin homology domain-containing protein 1 protein (1-105AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，LRCH1 Antibody (CSB-PA897471LA01HU)，的标记方式是Non-conjugated。对于LRCH1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA897471LB01HU LRCH1 Antibody, HRP conjugated ELISA
    FITC CSB-PA897471LC01HU LRCH1 Antibody, FITC conjugated
    Biotin CSB-PA897471LD01HU LRCH1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration.
  • 基因功能参考文献：
    1. In the analysis of hip osteoarthritis cases with superior maximum joint space narrowing (JSN) versus cases with non-superior maximum JSN we detected association with a variant in the LRCH1 gene. PMID: 27974301
    2. Letter: Did not observe an association between LRCH-1 SNPs and knee osteoarthritis. PMID: 22325041
    3. A genetic variant in LRCH1 was consistently associated with knee osteoarthritis in 3 samples from 2 populations. PMID: 16447229
    4. results suggest that there is no association between LRCH1 and knee osteoarthritis susceptibility PMID: 18049793
  • 亚细胞定位：
    Cytoplasm.
  • 数据库链接：

    HGNC: 20309

    OMIM: 610368

    KEGG: hsa:23143

    STRING: 9606.ENSP00000374447

    UniGene: Hs.507971