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LPTD Antibody

  • 货号：
    CSB-PA327058XA01ENV
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: LPTD antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 26.3 kDa
      Observed band size: 28.1 kDa
  • 其他：

产品详情

  • Uniprot No.：
    P31554
  • 基因名：
    LPTD
  • 别名：
    LPS-assembly protein LptD (Organic solvent tolerance protein) lptD imp ostA yabG b0054 JW0053
  • 反应种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 免疫原：
    Recombinant Escherichia coli (strain K12) LPTD protein
  • 免疫原种属：
    Escherichia coli (strain K12)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Protein G
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Contributes to n-hexane resistance.
  • 基因功能参考文献：
    1. These results demonstrate that multiple periplasmic proteases monitor outer membrane proteins at distinct points in the assembly process as in the case of degradation of the outer membrane protein LptD by the DegP, BepA and YcaL proteases. PMID: 28784813
    2. the mutant protein lptD4213 is synthetically lethal with the deletion of dsbB as well as with DsbB inhibitors PMID: 28232484
    3. findings suggest lptE14 causes poor plugging of the LptD beta barrel and that a reduction of ineffectively plugged LptD-LptE14 complexes in the outer membrane decreases permeability to erythromycin; lptE14 supports a proposed plug-and-barrel LptE-LptD arrangement PMID: 23316047
    4. disulfide bond-dependent protein folding of LptD requires the proper assembly of a two-protein complex to promote disulfide bond rearrangement. PMID: 22936569
    5. Data show that oxidation of LptD is not required for the formation of the LptD/E complex but it is essential for function. PMID: 20566849
    6. LptD contains a soluble N-terminal domain and a C-terminal transmembrane domain. LptE stabilizes LptD by interacting with the C-terminal domain of LptD. LptE binds LPS specifically and may serve as a substrate recognition site at the outer membrane. PMID: 20203010
    7. Results show that RlpB is essential for cell viability and that the Imp/RlpB complex is responsible for lipopolysaccharides reaching the outer surface of the outer membrane. PMID: 16861298

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  • 亚细胞定位：
    Cell outer membrane.
  • 蛋白家族：
    LptD family
  • 数据库链接：

    KEGG: ecj:JW0053

    STRING: 316385.ECDH10B_0055