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LILRB5 Antibody

  • 货号：
    CSB-PA006750
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    O75023
  • 基因名：
  • 别名：
    LILRB5; LIR8; Leukocyte immunoglobulin-like receptor subfamily B member 5; CD85 antigen-like family member C; Leukocyte immunoglobulin-like receptor 8; LIR-8; CD antigen CD85c
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human CD85c.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May act as receptor for class I MHC antigens.
  • 基因功能参考文献：
    1. The transcriptional profile of the orphan receptor LILRB5 is significantly up-regulated following exposure to mycobacteria. PMID: 26908331
    2. LILRB5 binding to intracellular HLA-class I heavy chains suggests a chaperone function PMID: 26098415
    3. The rs12975366 in the LILRB5 gene was significantly associated with CK levels of statin users. PMID: 25214527
    4. Mature cord-blood-derived mast cells expressed LILRB5 in cytoplasmic granules and upon cross-linking of the high-affinity IgE receptor, released LILRB5 into the culture medium. PMID: 17998301
  • 亚细胞定位：
    Membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Detected in a natural killer (NK) cells.
  • 数据库链接：

    HGNC: 6609

    OMIM: 604814

    KEGG: hsa:10990

    STRING: 9606.ENSP00000406478

    UniGene: Hs.655338