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LDHC Antibody

  • 货号：
    CSB-PA012844GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    P07864
  • 基因名：
  • 别名：
    Cancer/testis antigen 32 antibody; CT32 antibody; EC 1.1.1.27 antibody; L lactate dehydrogenase C chain antibody; L-lactate dehydrogenase C chain antibody; Lactate Dehydrogenase C antibody; Lactate dehydrogenase c variant 1 antibody; Lactate dehydrogenase c variant 3 antibody; Lactate dehydrogenase c variant 4 antibody; Lactate dehydrogenase C4 antibody; LDH C antibody; LDH testis subunit antibody; LDH X antibody; LDH-C antibody; LDH-X antibody; LDH3 antibody; ldhc antibody; LDHC_HUMAN antibody; LDHX antibody; MGC111073 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Human LDHC
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Possible role in sperm motility.
  • 基因功能参考文献：
    1. Lactate dehydrogenase C may act as a novel biomarker for renal cell carcinoma progression and a potential therapeutic target for the treatment of renal cell carcinoma. PMID: 28351304
    2. three uniquely identified proteins (CDK6 , galectin-3-binding protein and LDH C) were found, which show tight connection with prostate cancer and presence of all of them was previously linked to certain aspects of prostate cancer PMID: 26503549
    3. Down-regulated LDH-C4 expression is significantly correlated with lowered enzyme activity in human spermatozoa. PMID: 25795631
    4. This is the first report to show a positive correlation between LDH-3 and hemolytic parameters in sickle cell anemia. PMID: 26069337
    5. LDH3 was increased in essential thrombocythemia. This isoenzymatic pattern could be expression of a metabolic adaptation. PMID: 17178662
    6. LDH3 is a supporting diagnostic marker in cases of chronic tuberculosis. PMID: 17935709
    7. hLdhc expression in cancer cells was regulated by transcription factor Sp1 and CREB and promoter CGI methylation PMID: 18930904

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    LDH/MDH superfamily, LDH family
  • 数据库链接：

    HGNC: 6544

    OMIM: 150150

    KEGG: hsa:3948

    STRING: 9606.ENSP00000280704

    UniGene: Hs.654377