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KYAT1 Antibody

  • 货号：
    CSB-PA613699LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA613699LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA613699LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) KYAT1 Polyclonal antibody
  • Uniprot No.：
    Q16773
  • 基因名：
    KYAT1
  • 别名：
    KYAT1 antibody; CCBL1 antibody; Kynurenine--oxoglutarate transaminase 1 antibody; EC 2.6.1.7 antibody; Cysteine-S-conjugate beta-lyase antibody; EC 4.4.1.13 antibody; Glutamine transaminase K antibody; GTK antibody; Glutamine--phenylpyruvate transaminase antibody; EC 2.6.1.64 antibody; Kynurenine aminotransferase 1 antibody; Kynurenine aminotransferase I antibody; KATI antibody; Kynurenine--oxoglutarate transaminase I antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Kynurenine--oxoglutarate transaminase 1 protein (1-372AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，KYAT1 Antibody (CSB-PA613699LA01HU)，的标记方式是Non-conjugated。对于KYAT1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA613699LB01HU KYAT1 Antibody, HRP conjugated ELISA
    FITC CSB-PA613699LC01HU KYAT1 Antibody, FITC conjugated
    Biotin CSB-PA613699LD01HU KYAT1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. Also metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond.
  • 基因功能参考文献：
    1. Immunohistochemical analysis revealed the presence of KAT I, II, and III in all examined corneal sections. PMID: 28706436
    2. CH(3)Hg-S-Cys and Cys-S-Hg-S-Cys are substrates and reversible inhibitors of GTK. PMID: 22093698
    3. major biological roles of glutamine transaminase K are to maintain low levels of phenylpyruvate and to close the methionine salvage pathway--REVIEW PMID: 15016471
    4. We found elevated cerebellar KAT-1 activities in post-mortem brain samples from schizophrenic versus normal individuals. PMID: 16828464
    5. alpha-keto acids generated by transamination/l-amino acid oxidase activity of the two catechol cysteine S-conjugates are unstable PMID: 18342615

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  • 亚细胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    Class-I pyridoxal-phosphate-dependent aminotransferase family
  • 数据库链接：

    HGNC: 1564

    OMIM: 600547

    KEGG: hsa:883

    STRING: 9606.ENSP00000302227

    UniGene: Hs.495250