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KRT6C Antibody

  • 货号：
    CSB-PA216033
  • 规格：
    ￥2024
  • 图片：
    • Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using.
    • Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) KRT6C Polyclonal antibody
  • Uniprot No.：
    P48668
  • 基因名：
    KRT6C
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide corresponding to a region derived from internal residues of Human keratin 6C
  • 免疫原种属：
    Homo sapiens (Human)
  • 克隆类型：
    Polyclonal
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:50-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Several missense polymorphisms in KRT6A, KRT6B and KRT6C that lead to a higher risk for dental caries. PMID: 29357356
    2. report on a novel mutation of KRT6C and highlight the inclusion of focal PPK secondary to KRT16 and KRT6C mutations as a milder phenotype within the spectrum of PC PMID: 26301947
    3. mutation c.1414G>A resulting in an p.Glu472Lys substitution associated with focal plantar keratoderma PMID: 23662636
    4. Keratin K6c mutations cause focal palmoplantar keratoderma PMID: 19609311
    5. KRT6C mutations may have a role in focal palmoplantar keratoderma [commentary] PMID: 20081885

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  • 相关疾病：
    Palmoplantar keratoderma, non-epidermolytic, focal or diffuse (PPKNEFD)
  • 蛋白家族：
    Intermediate filament family
  • 组织特异性：
    Constitutively expressed in distinct types of epithelia such as those in oral mucosa, esophagus, papillae of tongue and hair follicle outer root sheath.
  • 数据库链接：

    HGNC: 20406

    OMIM: 612315

    KEGG: hsa:286887

    STRING: 9606.ENSP00000252250

    UniGene: Hs.700779